发明名称 |
Method of selection for spiramycin resistance in streptomyces |
摘要 |
A novel method of selecting Streptomyces recombinant DNA-containing host cells and vectors useful in the method are described. The vectors confer spiramycin resistance to sensitive Streptomyces host cells and thus provide a convenient method of selecting Streptomyces transformants. The novel spiramycin resistance-conferring gene described can be isolated on an DIFFERENCE 3.8 kb Bc1I restriction fragment from plasmid pNAS105. Plasmid pNAS105 can be isolated from Streptomyces griseofuscus C581/pNAS105 (NRRL 15919).
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申请公布号 |
US4753880(A) |
申请公布日期 |
1988.06.28 |
申请号 |
US19840685677 |
申请日期 |
1984.12.24 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
SCHAUS, NANCY A.;SOLENBERG, PATRICIA J. |
分类号 |
C12N15/65;C12N15/76;(IPC1-7):C12N15/00;C12N1/20;C07H15/12 |
主分类号 |
C12N15/65 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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