发明名称 NOVEL NAPHTHOQUINONE BASED COMPOUND NQY
摘要 NEW MATERIAL:A compound expressed by the formula having the following properties; appeArance, yellow powder; melting point, 160-170 deg.C (decomposed); [alpha]D<24>=-96 deg. (C=0.002, CHCl3); molecular formula, C20H2OO7; highly resolving power EI mass spectrum (m/z), 372 and 1224; solubility, soluble in chloroform, methanol and acetone and insoluble in ethyl ether and water, etc. USE:An inhibiting agent of cancer metastasis. PREPARATION:A bacterium strain [e.g. Streptomyces malachiticus No. S-1998 strain (FERM P-8961), etc.] belonging to the genus Streptomyces malachiticus and having NQY-producing ability is cultured preferably by an aerobic liquid submerged cultivation at 25-30 deg.C for 72-96hr.
申请公布号 JPS63122687(A) 申请公布日期 1988.05.26
申请号 JP19860267982 申请日期 1986.11.11
申请人 KIRIN BREWERY CO LTD 发明人 OTAKE NOZOMI;KOBAYASHI EIICHI;IWAKIRI TAKAFUMI;IMAMURA KANJI
分类号 C07D493/08;A61K31/35;A61P35/00 主分类号 C07D493/08
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