发明名称 |
A PROCESS AND AN AGENT FOR DETECTION OF GENE STRUCTURES IN HUMANS HAVING A GREAT TENDENCY TO DEVELOP IDDM |
摘要 |
An agent for detection of gene structures which are characteristic of humans having a tendency to develop insulin-dependent diabetes mellitus (IDDM), consisting of or containing a DNA sequence from the HLA-DG beta -chain gene with 154 bp from intron 1 (IVS1) and adjoining first 12 bp of exon 2 or a reactive fragment thereof. There is moreover disclosed a process for identification of said DNA structure by hybridization of chromosomes from the individual to be tested with the agent in a labelled stated and detection of the labelled hybrid. |
申请公布号 |
AU8155187(A) |
申请公布日期 |
1988.05.06 |
申请号 |
AU19870081551 |
申请日期 |
1987.10.15 |
申请人 |
NORDISK INSULINLABORATORIUM, |
发明人 |
BIRGITTE MICHELSEN;AKE LERNMARK |
分类号 |
C07K14/74;C12Q1/68;G01N33/50 |
主分类号 |
C07K14/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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