发明名称 (SUBSTITUTED-PHENYL)-5-OXO-PYRROLIDINE-2-PROPANOIC ACIDS AND DERIVATIVES AS COGNITION ACTIVATORS
摘要 <p>Certain 5-oxo-3-(unsubstituted-phenyl)- or 5-oxo-3- (substituted-phenyl)-2-pyrrolidinepropanoic acids and 5-oxo-.beta.- (unsubstituted-phenyl)- or 5-oxo-.beta.-(substituted-phenyl)-2-pyrrolidinepropanoic acids, their pharmaceutically acceptable esters and metal and amine cation salts, pharmaceutical compositions employing these compounds, and a method of treating senility or of reversing amnesia are disclosed. The compounds have the general formula: (I) or (II) wherein * represents an asymmetrical carbon center, R represents H, phenyl, phenylmethyl or C1-6alkyl, and X and Y, independently, represent H, Cl, -CF3, C1-6alkyl or C1-6alkoxy.</p>
申请公布号 CA1235706(A) 申请公布日期 1988.04.26
申请号 CA19850478994 申请日期 1985.04.12
申请人 WARNER-LAMBERT COMPANY 发明人 BUTLER, DONALD E.;THOMAS, ANTHONY J.
分类号 A61K31/40;A61K31/4015;A61P25/28;C07D207/26;(IPC1-7):C07D207/267 主分类号 A61K31/40
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