发明名称 CYCLIC AMINE DERIVATIVES
摘要 Heterocyclic amines of formula (I) and their salts are new: where A is (opt. substd.) phenyl or naphthyl, pyridyl, thienyl, tetralyl, quinolinyl, benzofuranyl, quinazolinyl, benzothienyl, 1,2,3,4-tetrahydro-2-quinolinyl or 1-oxo-1,2,3,4-tetrahydro -2-naphthyl; X is -CH2, -CO-, -CHOH-, -CHMe- or -CH(CH2NEt2)-; m is 1-3; n is 0-4; Y is C or N; Z is -CH2-, -CO-, -CHOR1-, -CHHal-, -CH=, or a group of formula (II), (III) or (IV); R1 is H, lower alkyl, acyl, aralkyl or heteroaralkyl, Hal is halogen; B is phenyl or naphthyl opt. substd. by one or two groups chosen from halogen, lower alkyl or lower alkoxy; Z-B may be bound at either of the positions starred on the ring.
申请公布号 AU6405486(A) 申请公布日期 1988.04.21
申请号 AU19860064054 申请日期 1986.09.30
申请人 EISAI CO., LTD., 发明人 HACHIRO SUGIMOTO;TAKAHARU NAKAMURA;NORIO KARIBE;ISAO SAITO;KUNIZO HIGURASHI;MASAHIRO YONAGA;TAKERU KANEKO;TAKAHIRO NAKAZAWA;MASATAKA UENO;KIVOMI YAMATSU
分类号 A61K31/445;A61K31/47;C07D211/14;C07D211/16;C07D211/18;C07D211/22;C07D211/32;C07D211/70;C07D295/02;C07D295/03;C07D295/18;C07D295/192;C07D401/06;C07D405/04;C07D405/06;C07D409/04 主分类号 A61K31/445
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