发明名称 Analytical utilization of phagocyte cell lines
摘要 The property of phagocyte cells to show chemiluminescence when activated by certain chemical or immunological agents is used for a qualitative and quantitative analysis of such agents in biological fluids. A variety of factors such as opsonizing anti-bodies, complement, inhibitors, membrane-specific anti-bodies, and their antigens, membrane-specific lectins, lymphokines, endotoxins, toxic substances and others can be analyzed in this way. The new method finds application in the biotechnical, clinical, immunological and pharmacological fields, with a special preference for toxicological screening of pharmaceuticals. The phagocyte cells needed for the analysis can be derived from a continuous phagocyte cell line and a method of producing such a cell line is provided.
申请公布号 US4737455(A) 申请公布日期 1988.04.12
申请号 US19850723100 申请日期 1985.04.15
申请人 N.V. INNOGENETICS 发明人 DE BAETSELIER, PATRICK
分类号 G01N33/52;A61K35/12;A61K35/28;A61K38/16;C12N5/02;C12N5/10;C12N5/16;C12N15/02;C12P21/08;C12Q1/02;C12R1/91;G01N33/50;G01N33/577;(IPC1-7):C12N5/00;G01N33/567;G01N33/569 主分类号 G01N33/52
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