Förfarande för framställning av farmaceutiskt värdefull 7 -/(Z)-2-(2-a minotiazol/-4-yl)-2-oxi-imino-acetamido/-3-cefem-4-karboxylsyra.

摘要

A cephalosporin compound of the formula: wherein R<1> is hydrogen or lower alkyl; R<2> is acetoxy or (1-methyl-1H-tetrazol-5-yl)thio, and R<3> is carboxy; or R<2> is a group of the formula:- R<3> is -COO<-> and Y is hydrogen, hydroxymethyl or carbamoyl; and n is an integer of 2 or 3, or a pharmaceutically acceptable salt thereof and processes for their preparation are disclosed. The cephalosporin compound and the salt are useful as anti-microbial agents.