摘要 |
<p>Hybrid interferon polypeptide (I) has an aminoacid sequence composed of 2-4 sub-sequences corresp. in aminoacid identity and number to sub-sequences of human lymphoblastoid interferons LyIFN-alpha-2 and LyIFN-alpha-3. (I) has the aminoacid sequence of aminoacids 1-150 of -alpha-2, and 151-166 of -alpha-3; aminoacids 1-92 of -alpha-2, 93-150 of -alpha-3 and 151-166 of -alpha-2; or aminoacids 1-60 of alpha-2, 61-92 of -alpha-3, 93-150 of -alpha-2 or -alpha-3 and 151-166 of -alpha-2 or -alpha-3. Also claimed are the monoclonal antibody 144BS and its derivs. and the hybridoma cell line 144BS 22-6-19, number I-424.</p> |