发明名称 |
Peptide, process for preparation thereof and use thereof |
摘要 |
The invention concerns peptides, having the pharmaceutical property of enhancing the immune response, having the structure: <IMAGE> wherein R1 is alkanoyl, Rb1 is hydrogen, methyl, isopropyl, hydroxymethyl, protected hydroxymethyl or benzyl, R2 is hydrogen, carboxy, protected carboxy or a group of the formula: <IMAGE> wherein Ra2 is mono- or di-carboxy (or protected carboxy) lower alkyl or ar(carboxy or protected carboxy) lower alkyl whose aryl moiety is substituted by hydroxy or not substituted, Rb2 is hydrogen or lower alkyl, Rp is hydrogen, carboxy or protected carboxy, Rq is carboxy, protected carboxy or a group of the formula <IMAGE> wherein Ra2 and Rb2 are each as defined above, Rr is hydrogen or amino protective group, m is an integer 1 to 3, and n is an integer 1.
|
申请公布号 |
US4725582(A) |
申请公布日期 |
1988.02.16 |
申请号 |
US19820377836 |
申请日期 |
1982.05.13 |
申请人 |
FUJISAWA PHARMACEUTICAL COMPANY, LTD. |
发明人 |
KITAURA, YOSHIHIKO;NAKAGUCHI, OSAMU;HEMMI, KEIJI;ARATANI, MATSUHIKO;HIDEKAZU, TAKENO;OKADA, SATOSHI;TANAKA, HIROKAZU;HASHIMOTO, MASASHI;KURODA, YOSHIO;IGUCHI, EIKO;KOHSAKA, MASANOBU;AOKI, HATSUO;IMANAKA, HIROSHI |
分类号 |
A61K38/00;C07K5/02;C07K5/06;C07K5/062;C07K5/072;C07K9/00;(IPC1-7):A61K37/02;C07C103/52 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|