发明名称 IN SITU ACTIVE COMPOUND ASSEMBLY
摘要 A composition for chemically treating a target condition, existing at a microenvironment localized within an environment, with an active compound, the composition comprising precursor components which can conjugate covalently to form the active compound in situ, and for which the covalent conjugation is more favourable at the microenvironment of the target condition than in the surrounding environment. Disclosed examples include biologically-active compounds which are preferentially formed in the microenvironment of tumour cells.
申请公布号 AU7750387(A) 申请公布日期 1988.01.29
申请号 AU19870077503 申请日期 1987.07.06
申请人 SCRIPPS CLINIC AND RESEARCH FOUNDATION, 发明人 DARRYL C. RIDEOUT
分类号 A61K31/16;A01N61/00;A61K9/00;A61K31/35;A61K31/40;A61K31/655;A61K45/00;A61K49/00;A61P35/00;A61P43/00 主分类号 A61K31/16
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