发明名称 |
Non-human Carbonyl hydrolase mutants, DNA sequences and vectors encoding same and hosts transformed with said vectors. |
摘要 |
Novel carbonyl hydrolase mutants derived from the amino acid sequence of naturally-occurring or recombinant non-human carbonyl hydrolases and DNA sequences encoding the same. The mutant carbonyl hydrolases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant carbonyl hydrolase to encode the substitution, insertion or deletion of one or more amino acids in the amino acid sequence of a precursor carbonyl hydrolase. Such mutants have one or more properties which are different than the same property of the precursor hydrolase. |
申请公布号 |
EP0251446(A2) |
申请公布日期 |
1988.01.07 |
申请号 |
EP19870303761 |
申请日期 |
1987.04.28 |
申请人 |
GENENTECH, INC. |
发明人 |
WELLS, JAMES ALLEN;CUNNINGHAM, BRIAN C.;CALDWELL, ROBERT MARK;BOTT, RICHARD RAY;ESTELL, DAVID AARON;POWER, SCOTT DOUGLAS |
分类号 |
C12N9/14;C11D3/386;C12N1/00;C12N1/20;C12N9/54;C12N9/56;C12N15/00;C12N15/09;C12R1/07;C12R1/19 |
主分类号 |
C12N9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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