发明名称 |
Alkylenediamine derivatives. |
摘要 |
<p>Novel alkylenediamine derivative having the formula (I): <CHEM> wherein A is a group having the formula (II): R<1>(CH2)m-CH(R<2>)-(CH2)n- (II) (wherein R<1> is an aliphatic hydrocarbon group, an alicyclic group, an aryl group, or an aralkyl group; R<2> is an aliphatic hydrocarbon group, en alkoxy group, an aliphatic hydrocarbon group containing an ester or ether bonding, or an aryloxy group; and each of m and n is an integer of 0 to 2, provided that m + n does not exceed 3) and B is hoydrogen, or A is a group having the formula (III): R<3>-(CH2)k- (III) (wherein R<3> has the same meaning as that of R<1> and k is an integer of 0 to 3) and B is a group repesenting by the formula (IV): R<4>- (IV) wherein R<4> has almost the same meaning as that of R<2>, p is an integer of 2 to 6, and q is an integer of 4 to 7. These compounds are useful as glutamate blockers.</p> |
申请公布号 |
EP0235942(A1) |
申请公布日期 |
1987.09.09 |
申请号 |
EP19870300850 |
申请日期 |
1987.01.30 |
申请人 |
NIPPON CHEMIPHAR CO., LTD. |
发明人 |
MASAKI, MITSUO;SHINOZAKI, HARUHIKO;SATOH, MASARU;MORTIOH, NAOYA;HASHIMOTO,KOICHI;KAMISHIRO, TOSHIRO |
分类号 |
C07D295/12;A61K31/132;A61K31/445;A61K31/55;A61P21/02;C07D295/13;(IPC1-7):C07D295/12;A61K31/395 |
主分类号 |
C07D295/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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