发明名称 |
Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease |
摘要 |
Hydroximic acids of 7-oxabicycloheptane substituted ether and thioether prostaglandin analogs are provided having the structural formula <IMAGE> wherein Y is O or <IMAGE> and including all stereoisomers thereof. The compounds are inhibitors of prostaglandin and biosynthesis and as such are useful, for example, as anti-allergy and antiinflammatory agents and also as antipsoriatic agents.
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申请公布号 |
US4673685(A) |
申请公布日期 |
1987.06.16 |
申请号 |
US19860888671 |
申请日期 |
1986.07.23 |
申请人 |
E. R. SQUIBB & SONS, INC. |
发明人 |
VARMA, RAVI K.;GORDON, ERIC M.;SIMPKINS, LIGAYA M. |
分类号 |
A61K31/34;A61K31/44;A61P1/04;A61P7/02;A61P9/08;A61P9/10;A61P9/12;A61P11/08;A61P17/00;A61P25/04;A61P29/00;A61P37/08;A61P43/00;C07D493/08;(IPC1-7):A61K31/34;A61K31/557;C07D307/00 |
主分类号 |
A61K31/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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