摘要 |
Novel alpha -aryl- alpha -( omega -aminoalkyl)- alpha -[hydroxy(aralkyl and cycloalkyl)]acetic acid derivatives and alpha -aryl- alpha -( omega -aminoalkyl)- alpha [alkanoyloxy(aralkyl and cycloalkyl)]acetic acid derivatives, such as N,N-dimethyl-2-(hydroxyphenylmethyl)-4-dimethylamino-2-phenylbutanamide, 2-(hydroxyphenylmethyl)-5-dimethylamino-2-phenylpentanenitrile, ethyl 2-(hydroxyphenylmethyl)-5-dimethylamino-2-phenylpentanoate, and N,N-dimethyl-2[(acetyloxy)phenylmethyl]-4-dimethylamino-2-phenylbutana mide, useful in the treatment of cardiovascular disease. |