摘要 |
<p>4-Oestrene derivs. of formula (I) and their 4,5-dihydro-5alphaH analogues are claimed for use as immunomodulators. R1 = (H,H) or O; R2 = (H,OR5) or O; R3 = (alpha-R6,beta-OR7); R4 = Me or Et; R5 = H or 1-4C alkyl; R6 = H or 1-4C hydrocarbyl; R7 = H or 1-18C acyl. Specifically R4 = Me; R5 = H or Me; R6 = H, Et or ethynyl; R7 = H.</p> |