Production of aminoalkylsulfonic acids

摘要

PCT No. PCT/JP83/00301 Sec. 371 Date May 2, 1984 Sec. 102(e) Date May 2, 1984 PCT Filed Sep. 8, 1982 PCT Pub. No. WO84/00958 PCT Pub. Date Mar. 15, 1984.Disclosed herein is a process for preparing with a high yield an aminoalkylsulfonic acid represented by the following general formula: <IMAGE> wherein R1, R2 and R3 are each a hydrogen atom, an alkyl group having 1-3 carbon atoms or a hydroxyl-containing alkyl group having 1-3 carbon atoms and n stands for an integer of 2 or 3, which process comprises reacting a sulfite with a halogenated alkylamine represented by the following general formula: <IMAGE> wherein X means a chlorine, bromine or iodine atom, and R1, R2, R3 and n have the same meanings as defined above by adding the halogenated alkylamine little by little either continuously or intermittently over a certain period of time to a heated aqueous solution of the sulfite. The yield may be increased further when, after the addition of the halogenated alkylamine, the reaction is carried out by raising the reaction temperature stepwise in 2-5 stages while limiting the reaction time and temperature-raising range in each stage to 0.5-4 hours and 10 DEG -20 DEG C.