| 摘要 |
<p>N1,N1-disubstd. derivs. of formula (I), in which R1 is H, lower alkoxy or nitro, R2 is lower alkyl, phenyl or phenyl alkyl and the aromatic rings are substd. with halogen, nitro or alkoxy, for use as anti-histamine agents, are made by reacting an isothiocyanate of formula (II) with a benzimidazole N-oxide of formula (III) in an inert solvent (CHCl3) through which bubbles a current of nitrogen, and at ambient temp.</p> |
