| 摘要 |
PURPOSE:A remedy, containing human erythropoietin as an active constituent and useful as a remedy for malignant tumorous anemia. CONSTITUTION:A remedy containing human erythropoietin as an active constituent. The erythropoietin (hereinafter abbreviated to EPO) is a glycoprotein mainly produced in the kidney and known as a humoral hematopoietic factor having action of affecting erythroblastic stem cells present in marrow to promote the differentiation to erythrocytic cells, but is found to be effective for treating anemia in animals with cancer. The human EPO can be obtained by various means and examples thereof include methods of purification from human urine, gene expression of a gene coding amino acid sequence of the human EPO in a host cell, e.g. Escherichia coli, yeast, Chinese hamster, ovarian cell, COS cell, etc. The remedy is normally administered by a method for administering the human EPO pharmaceutical containing 0.1-500mug EPO per adult 1-7times/ week. |
