发明名称 VINYL DERIVATING AND 5-LIPOXIGENASE INHIBITOR CONTAINING SAME
摘要 NEW MATERIAL:The compound of formula I [(R)<m> is 3,4-dihydroxy, 3-methoxy-4- hydroxy, 3,4,5-trimethoxy, etc.; is number of double bonds having trans- configuration and is 1 or 2; Y is group of formula II (l is 2 or 3), group of formula III (X is H, halogen or methoxy; K is 2 or 3), etc.]. EXAMPLE:1-[3-{3-(3-Methoxy-4-hydroxyphenyl)-2-propenyloxy}-propyl]-4-( benzhy dryloxy)piperidine. USE:Antiallergic agent. PREPARATION:The compound of formula I can be produced by condensing the alcohol derivative of formula IV (n is 0 or 1) with the piperidine derivative of formula V and removing the protecting group from the condensation product.
申请公布号 JPS61254559(A) 申请公布日期 1986.11.12
申请号 JP19850096385 申请日期 1985.05.07
申请人 TERUMO CORP 发明人 TAKAI MAKOTO;ITOU NORIIE;WAKABAYASHI TOSHIO;MUROTA SEIITSU
分类号 C07D211/46;A61K31/445;A61K31/495;A61P37/08;A61P43/00;C07D295/08;C07D295/10 主分类号 C07D211/46
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