摘要 |
NEW MATERIAL:The compound of formula I [(R)<m> is 3,4-dihydroxy, 3-methoxy-4- hydroxy, 3,4,5-trimethoxy, etc.; is number of double bonds having trans- configuration and is 1 or 2; Y is group of formula II (l is 2 or 3), group of formula III (X is H, halogen or methoxy; K is 2 or 3), etc.]. EXAMPLE:1-[3-{3-(3-Methoxy-4-hydroxyphenyl)-2-propenyloxy}-propyl]-4-( benzhy dryloxy)piperidine. USE:Antiallergic agent. PREPARATION:The compound of formula I can be produced by condensing the alcohol derivative of formula IV (n is 0 or 1) with the piperidine derivative of formula V and removing the protecting group from the condensation product. |