| 摘要 |
PURPOSE:To provide a composition for the application to cuticle, containing a lower alcohol, a component selected from a group of specific compounds and water, capable of effectively promoting the transcutaneous absorption of drug and usable as a base of medicinal drug. CONSTITUTION:The objective composition contains (A) a lower alcohol (e.g. ethyl alcohol, propyl alcohol, etc.), (B) a compound selected from 7-20C alcohol (e.g. n-heptyl alcohol, lauryl alcohol, etc.), 5-30C aliphatic hydrocarbon (e.g. n-pentane, n-hexane, etc.), an alcohol ester of 19-26C aliphatic carboxylic acid (e.g. methyl stearate, ethyl linolate, etc.), etc., and (C) water. The ratio of (A+C):B is 90:1-50:50, and that of A:C is preferably 30:70-70:30. A drug can be absorbed transcutaneously in high efficiency by applying the drug to the cuticle in the presence of the above composition.
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