EPIDERMAL GROWTH FACTOR PRODUCTION AND METHOD TO DEPILATE ANIMALS SUCH AS SHEEP

摘要

A DNA sequence encoding a fusion protein comprising a carrier protein linked through a Lys residue to an EGF or EGF analogue, which EGF or EGF analogue does not contain an internal Lys residue and from which fusion protein the EGF or EGF analogue is cleavable by a Lys-specific protease, is incorporated in a vector which is capable, in a transformed host, of expressing the fusion protein. The EGF or EGF analogue is released from the fusion protein by treatment with a Lys-specific protease. The EGF or EGF analogue is useful for depilating animals, especially defleecing sheep.