摘要 |
NEW MATERIAL:The compound of formula I {R<1> is COR<3> [R<3> is OH, 1-4C alkoxy, NHR<4> (R<4> is H, amino, phenylamino, amido, etc.) or morpholino] or SO2R<5> (R<5> is 1-3C alkyl or phenyl); R<2> is H, cyano, amido, NHCOR<6> (R<6> is 1-3C alkyl or phenyl), etc.} and its salt. USE:Synthetic intermediate for antiallergic agent and organic compounds. PREPARATION:The compound of formula II (R<8> is H, cyano, amido, etc.) can be produced e.g. by reacting 3,5-diisopropyl-4-hydroxybenzaldehyde with the compound having the group of formula R<1>-CH2-R<9> (R<9> is H, carboxyl, cyano, amido, etc.) in the presence of a basic catalyst (e.g. aniline, pyridine, etc.). |