发明名称 |
7-AMINO-O-2-ISOCEPHEM-4-CARBOXYLIC ACID COMPOUND AND MANUFACTURE |
摘要 |
There is described novel substituted DELTA 2,3-1, 4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula <IMAGE> wherein Q is hydrogen or alkyl and X is amino. Also included in the invention are compounds of the above formula in which the carboxyl group at the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds. The compounds and their physiologically hydrolyzed esters and pharmaceutically acceptable salts are useful as intermediates in the preparation of antibacterial agents. |
申请公布号 |
JPS61197587(A) |
申请公布日期 |
1986.09.01 |
申请号 |
JP19850163074 |
申请日期 |
1985.07.25 |
申请人 |
BRISTOL MAYERS CANADA LTD |
发明人 |
BERUNARUDO AARU BERIYUU;TERENSU DABURIYUU DOIRU;BINGU YUU RUU;TERII TEI KONUEI |
分类号 |
C07D205/08;A61K31/397;A61K31/535;A61P31/04;B01J23/00;B01J25/00;B01J31/00;C07B61/00;C07D205/085;C07D257/04;C07D317/30;C07D498/04;C07D505/00;C07D507/04;C07D507/06;C07D507/08 |
主分类号 |
C07D205/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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