发明名称 BIS-IMIDAZOLINOAMINO DERIVATIVE AS EFFECTIVE ANTIALLERGIC COMPOUND
摘要 Compounds possessing valuable therapeutic activity particularly as lipoxygenase inhibitors possessing anti-inflammatory and anti-allergic properties, of the formula: <IMAGE> wherein Z is an unsubstituted normal alkylene chain of up to 8 carbon atoms or a substituted normal alkylene chain in which the substituent is lower alkyl, phenyl or benzyl containing up to 8 carbon atoms in the normal chain and up to a total of about 12 carbon atoms; X=O to S; n=0 or 1; and each R is H, lower alkyl or lower alkanoyl; and salts thereof, especially pharmaceutically-acceptable salts.
申请公布号 JPS61152644(A) 申请公布日期 1986.07.11
申请号 JP19850285888 申请日期 1985.12.20
申请人 USV PHARMACEUT CORP 发明人 FUU CHII HANGU
分类号 A61K31/415;A61K31/505;A61P11/00;A61P37/08;C07C67/00;C07C213/00;C07C217/76;C07C239/00;C07C253/00;C07C255/13;C07C255/46;C07C255/54;C07C279/04;C07C279/18;C07C279/28;C07C313/00;C07C323/12;C07C323/29;C07D233/50;C07D239/14;C07D307/10;C07D307/14;C07D405/12;C07D405/14;C12N9/99 主分类号 A61K31/415
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