| 摘要 |
NEW MATERIAL:The compound of the formula or its acid adducts. It has follow ing physical and chemical properties: A reddish brown powder; elementary analyses in %: C 61.58, H 6.42, N 2.17, O 29.83; melting point: 105-110 deg.C; [alpha]<21>D=+78 deg. (C=0.1 in methanol); molecular weight: m/z 644 (M+H)<+>; molecular formula: C33H41NO12; solubility: soluble in acidic water, basic water, methanol, ethanol, n-propanol, n-butanol, acetone, ethyl acetate, chloroform; insoluble in water, hexane, cyclohexane, petroleum ether; yellow in methanol solution, while violet in alkaline solution. USE:Antitumor agent with low toxicity. PREPARATION:For example, actinomadura roseoviolacae Ru7062 (FERM-8005) is preferably cultured by the aerobic liquid submerge cultivation at 35-37 deg.C usually for 4-5 days. |
