| 摘要 |
PURPOSE:To provide the titled lotion containing kojic acid as an active component, effective to suppress the formation of melanin by inhibiting the action of tyrosinase existing in the skin, and capable of sufficiently preventing the spot, lentigo, macula, etc. caused by the deposition of melanin pigment. CONSTITUTION:The objection lotion can be prepared by using a kojic acid selected from (A) pure kojic acid, (B) a fermentation liquid composed mainly of kojic acid and prepared by culturing a kojic acid-producing microorganisms belonging to Aspergillus genus, Penicillium genus, Escherichia genus, Acetobacter genus and Gluconobacter genus, and (C) kojic acid extracted and crystallized from said fermentation liquid, as an active component, and adding the compo nent to a lotion composed of conventional base agent in an amount of 0.1-10.0 wt%, preferably 1.0-5.0 wt%. The obtained lotion for suppressing the melanin formation is non-toxic, free from undesirable effect to human body, and exhibits the above effects by the absorption of the active component into the skin when the lotion is applied to or rubbed into the skin. |
