| 摘要 |
PURPOSE:To produce efficiently piperidine useful as a raw material for drugs, agricultural chemicals, or rubber chemicals, etc., by hydrogenating catalytically tetrahydrofurfurylamine by the use of a ruthenium group catalyst. CONSTITUTION:Tetrahydrofurfurylamine is catalytically hydrogenated by the use of a ruthenium group catalyst in the form of ruthenium metal, ruthenium oxide, etc. or in the form of these ruthenium components supported on a carrier (e.g., alumina, etc.) in a solvent preferably n-hexane, benzene, tertiary butyl alcohol etc. at 160-250 deg.C at about 3-60atom hydrogen partial pressure, to produce piperidine. An amount of the catalyst used is preferably 0.01-0.3pt.wt. based on the raw material. In the reaction system, a small amount of ammonia may be present in order to improve selectivity of the aimed reaction product. |
