Adenylate kinase and process for the production thereof

摘要

A heat-resistant adenylate kinase is described whose activity after an incubation in a buffer solution at about 50 DEG C. for about 15 minutes is at least about 80% of the original activity prior to the incubation. This adenylate kinase can be obtained by cultivating a bacterium belonging to the genus Bacillus and collecting adenylate kinase from the resulting culture broth. This heat-resistant enzyme is very stable against heat and, therefore, after isolation, it can be stored for a long period of time compared with the conventional adenylate kinase.