发明名称 Histargin-related compounds, a process for their preparation and their use as medicaments.
摘要 <p>The present invention relates to compounds of the formula <CHEM> wherein A is a residual group obtained by removing one hydrogen atom from the alpha-amino group in an alpha-amino acid (excluding arginine) or a lower alkyl ester thereof; R is a hydrogen atom or a lower alkyl group, or a salt thereof, and to a process for the preparation of these compounds. The compounds are capable of inhibiting the action of angiotensin converting enzyme and can therefore be used as anti-hypertensive agents.</p>
申请公布号 EP0175180(A1) 申请公布日期 1986.03.26
申请号 EP19850110756 申请日期 1985.08.27
申请人 MICROBIAL CHEMISTRY RESEARCH FOUNDATION 发明人 UMEZAWA, HAMAO, PROF.;TAKEUCHI, TOMIO;AOYAGI, TAKAAKI;IINUMA, HIRONOBU;OGAWA, KEIJI;MORIGUCHI, MAKOTO;UMEDA, YOSHIHISA;KURODA, HIROYUKI;NAKAMURA, TERUYA;OHBAYASHI, AKIRA
分类号 A61K31/415;A61P9/12;A61P43/00;C07D233/54;C07D233/64;(IPC1-7):C07D233/64 主分类号 A61K31/415
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