发明名称 |
CONSTANT RELEASE RATE SOLID ORAL DOSAGE FORMULATIONS OF DRUGS HAVING A PK.SUB.A7-10 AND AN AQUEOUS SOLUBILITY OF 15-100 G/ML WATER |
摘要 |
<p>A constant order release rate solid oral dosage formulation of a drug having a pka 7-10 and a water solubility of from 15-100g/ml water, said formulation comprising: a therapeutically effective amount of a said drug; from about 0.5 to 6.0 weight percent of an acidretardant or hydrophobic cellulose derivative; from about 2.5 to 35 weight percent of a hydrogenated vegetable oil: from about 1 to 20 weight percent of an acrylic acid polymer; from about 0.5 to 4.0 weight percent of fumed silicon dioxide and from about 0.4 to 300 percent of a lubricant.</p> |
申请公布号 |
CA1201064(A) |
申请公布日期 |
1986.02.25 |
申请号 |
CA19830435148 |
申请日期 |
1983.08.23 |
申请人 |
VEREX LABORATORIES, INC. |
发明人 |
DUNN, JAMES M. |
分类号 |
A61K31/13;A61K9/20;A61K9/22;A61K9/26;A61K31/135;A61K31/275;A61K31/445;A61K31/50;A61P7/10;A61P9/04;(IPC1-7):A61K47/00 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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