| 摘要 |
<p>7-(alpha-(2-Amino-4-thiazolyl) -alpha-((2-amino-4-thiazolyl) methoxyimino) acetamido)-3-cephem -4-carboxylic acid derivs. of formula (I), their salts and their derivs. where at least one amino gp. and/or at least one carboxylic gp. is protected are new. (R=1-5C alkyl opt. substd. by 1-5C al acyloxy; 1-5C alkylthio 3-hydroxy-4-carboxy-5 -isothiazolylthiomethyl; or a gp. of formula (a)-(d); R=H or 1-5C alkyl; R2=H, (CH2)mCOOH, (CH2)mOH, (CH2)mNH2, (CH2)mSO3H or CONHR3; R3=H, OH or (CH2)nCOOH; M=0-3). 7-(alpha-(2-amino-4-thiazolyl) -alpha-((2-amino-4-thiazolyl) methoxyimino) acetamido) -3-(Q-1-pyridinomethyl) -3-cephen-4-carboxylate where Q=3-amino (cpd. (Ia)) and 4-amino are specifically claimed.</p> |
