N-benzoyl-N'-pyridazinyloxyphenyl urea compounds, and antitumorous compositions containing them, and process for their preparation.

摘要

An N-benzoyl-N'-pyridazinyloxyphenyl urea compound having the formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="15" wi="99" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein each of X<Sub>1</Sub> and X<Sub>2</Sub> is a hydrogen atom, a halogen atom or a nitro group, Y is a hydrogen atom, a halogen atom or a methyl group which may be substituted by fluorine, and Z is a hydrogen atom, a halogen atom or a trifluoromethyl group, provided that when X<Sub>l</Sub> is a hydrogen atom and X<Sub>2</Sub> is a hydrogen atom or a halogen atom, Y is a methyl group which may be substituted by fluorine and/or Z is a hydrogen atom or a trifluoromethyl group. The compound is useful as an active ingredient for an antitumorous composition.