发明名称 1-ALKYL-SUBSTITUTED 1,4-DIHYDROPYRIDINELACTONES,A PROCESS FOR THEIR PREPARATION,AND THEIR USE IN MEDICAMENTS
摘要 1. Dihydropyridinelactones of the general formula I see diagramm : EP0158138,P14,F1 in which R represents halogen, alkyl having 1 to 10 C atoms or cyano, R**1 represents hydrogen, halogen or C1 -C10 -alkyl or C1 -C10 -alkoxy, R**2 represents a C1 -C20 straight-chain, branched or cyclic, saturated or unsaturated hydrocarbon radical which can optionally be interrupted by 1 or 2 oxygen atoms or -SOn - (n = 0, 1 or 2) and which can optionally be substituted by one or more fluorine, chlorine, bromine or iodine atoms, phenyl, -NO2 , -O-, NO2 , C3 -C12 -trialkylsilyl, -OH, -CN, amino, C1 -C6 -monoalkylamino, dialkylamino in which each alkyl is C1 -C6 , or benzyl-C1 -C6 -alkyl-amino, R**3 represents hydrogen, NH2 , CHO, CN or a C1 -C8 straight-chain or branched, saturated or unsaturated hydrocarbon radical which can be interrupted in the chain by oxygen, -NH- or -N-alkyl (1 to 6 C atoms), and R**4 represents a C1 -C10 straight-chain or branched alkyl or C2 -C10 -alkenyl radical which can optionally be interrupted by one or two oxygen atoms in the alkyl chain and which can optionally be substituted by one to six fluorine atoms, Cl, br, I, CN, NH2 , OH, phenyl, naphtalyl, hydroxycarbonyl, alkoxycarbonyl (1 to 10 C atoms in the alkoxy radical), -CHO, morpholino or C1 -C4 -dialkylamino, in the form of isomers, isomer mixtures, racemates and optical antipodes.
申请公布号 ZA8502172(B) 申请公布日期 1985.12.24
申请号 ZA19850002172 申请日期 1985.03.22
申请人 BAYER AKTIENGESELLSCHAFT 发明人 SIEGFRIED GOLDMANN;FRIEDRICH BOSSERT;HILMAR BISCHOFF;DIETER PETZINNA;WALTER PULS;KLAUS SCHLOSSMANN
分类号 A61K31/435;A61P3/08;A61P3/10;C07D211/90;C07D491/04;C07D491/048 主分类号 A61K31/435
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