| 摘要 |
<p>Novel 1,4-dihydropyridines of the fomula <IMAGE> in which R1 and R2 each independently is hydrogen, C1-C4-alkyl, C1-C12-alkoxy, C1-C4-halogenoalkoxy, halogen, nitro, C1-C4-halogenoalkyl, C1-C4-halogenoalkylmercapto, <IMAGE> in which Z is oxygen or sulphur, and R4 and R5 each independently is hydrogen, C1-C4-alkyl, C1-C6-alkoxy, halogen, C1-C4-halogenoalkyl, C1-C4-halogenoalkoxy or nitro, or R1 and R2, together with 2 C atoms of the phenyl ring, form the ring <IMAGE> X is oxygen, sulphur or the radical NR6, R6 is a C1-C6-alkyl group, A is a C2-C10-alkylene group, it being necessary that at least two C atoms are located in the alkylene chain which connects the carbonyloxy group to X, and R3 is a monosaccharide or disaccharide moiety or a protected monosaccharide or disaccharide moiety, or pharmaceutically acceptable addition salts thereof, which exhibit positive inotropic activity and are useful in treating circulatory disorders.</p> |
