发明名称 AZA-HETEROARYL COMPOUNDS AS PI3K-GAMMA INHIBITORS
摘要 The present invention provides aza-heteroaryl derivatives of Formula I: and pharmaceutically acceptable salts thereof, wherein X, Y, Z, A, W, R4, R5, and R6 are defined herein, that inhibit the activity of phosphoinositide 3-kinases-gamma (PI3Kϒ) and are useful in the treatment of diseases related to the activity of PI3Kϒ including, for example, autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.
申请公布号 WO2016130501(A1) 申请公布日期 2016.08.18
申请号 WO2016US17073 申请日期 2016.02.09
申请人 INCYTE CORPORATION 发明人 ZOU, Ge;COMBS, Andrew P.;BUESKING, Andrew W.
分类号 C07D401/14;A61K31/423;A61K31/428;A61K31/47;A61P9/00;A61P25/28;A61P35/00;A61P37/00;C07D413/04;C07D413/14;C07D417/14;C07D471/04 主分类号 C07D401/14
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