PROCEDIMIENTO DE OBTENCION DE 2, 6-DIMETIL-4-(3-NITROFENIL)-1, 4-DIHIDROPIRIDIN-3-CARBOXILATO DE ISOPROPILO-5-CARBOXILATO DE 2-METOXIETILO

摘要

phenyl) 1,4-dihydro pyridine 3,5-dicarboxylic acid ester with one isopropyl and one 2-methoxy ethyl ester gp. is made by trans-esterification of isopropyl or 2-methoxy ethyl 2,6-diemthyl 4-(3'-nitrophenyl) 1,4-dihydro pyridine dicarboxylate with 2-methoxy ethanol or isopropanol respectively. Reaction is in an inert non-alcoholic organic solvent in presence of an acid or basic catalyst at -20 to 140 deg. C. The 1,4-dihydro pyridine salt formed is treated with a basic inorganic medium.