发明名称 GUANINE DERIVATIVES
摘要 Compounds of formula …<CHEM>… and their pharmaceutically acceptable salts are disclosed. R1is O or S; R2 is bromine or NHR where R is hydrogen or COR5 where R5 is alkyl of 1-4 carbon atoms, aryl or arylalkyl; and X and Y are each independently halogen, alkyl of 1-4 carbon atoms, alkoxy of 1-4 carbon atoms, trifluoromethyl, hydroxy, CN, SOnR3, COOR3, NR3R4, in which R3 and R4 are each independently hydrogen or alkyl of 1-4 carbon atoms and n is 0, 1, 2 or 3, and Y is further chosen from hydrogen. Also disclosed are a process for producing the compounds and pharmaceutical compounds comprising the compounds. The compounds are useful for treating autoimmune diseases.
申请公布号 AU4021985(A) 申请公布日期 1985.10.03
申请号 AU19850040219 申请日期 1985.03.21
申请人 WARNER-LAMBERT CO. 发明人 JAGADISH C. SIRCAR;CATHERIN R. BRUNGARDT;CHARLES F. SCHWENDER
分类号 C07D473/00 主分类号 C07D473/00
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