摘要 |
The present invention relates to novel azetidinone derivatives of the general formula: <IMAGE> where n is 0 or 2, X is hydrogen, halogen, amino, alkylamino, benzylamino or acylamino, and Y is <IMAGE> R is lower alkyl, 2,2,2-trichloroethyl, or aralkyl; and M is hydrogen or alkali metal having beta -lactamase inhibiting activity. The derivatives of the present invention can be administered together with antibiotics having a beta -lactam ring as antibacterial agents against beta -lactamase producing bacteria. A method for synthesizing said azetidinone derivatives is also disclosed.
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