摘要 |
NEW MATERIAL:A chemically modified polysaccharide having a main chain comprising beta-1,3-glucopyranosyl group of formula I (wherein Glu is glucopyranosyl and the numbers are positions of bonding) as repeating unit and a second repeating unit of formula II (wherein m is 0-2) and/or a third repeating unit of formula III (wherein n is 0-2) bonded to the main chain. USE:Antineoplastic agents. PREPARATION:A Schiff base obtained by reacting an aldehyde-form beta-1,3-glucan having a main chain comprising beta-1,3-glucopyranosyl groups of formula I as repeating unit and a carbonyl group-containing repeating unit of formula IV and/or a repeating unit of formula III bonded to the main chain with hydroxyurea is reduced.
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