| 摘要 |
PURPOSE:To provide a drug delivery member having the adhesivity to the skin, the drug releasability, the rapid action, etc. as a pressure-sensitive adhesive, by compounding a water-insoluble polymer having stickiness at normal temperature with a specific water-soluble polymer, water, and a drug for transcutaneous absorption. CONSTITUTION:A water-insoluble polymer having stickiness at normal temperature (e.g. natural rubber, synthetic rubber, acrylic polymer, etc.) is compounded with a water-soluble polymer composed of a monomer having one ethylenic unsaturated double bond [e.g. PVA, poly(meth)acrylic acid, etc.] and/or a polysaccharide (e.g. starch, pullullan, etc.), water, and a drug for transcutaneous absorption (e.g. corticosteroid, analgesic antiinflammatory agent, etc.). The obtained pressure-sensitive adhesive layer is applied to a carrier to obtain the objective drug delivery member. An excellent drug action can be exhibited by the action of the water-soluble polymer, the polysaccharide and water to impart the adhesive layer with the characteristics of an aqueous gel, i.e. skin moisturizing effect, drug-releasing property, adhesivity, etc.
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