发明名称 |
Process for the production of substituted phosphonic and phosphinic acids and thiazolidinyl phosphonic and phosphinic acid ester intermediates |
摘要 |
There are prepared 1-amino-2-mercapto-2-methylpropyl phosphonic acid or 1-amino-2-mercapto-2-methylpropyl alkylphosphinic acids of the formula <IMAGE> in which Y is hydroxy or an alkyl group by reacting thiazoline-(3) with a phosphonic acid dialkyl ester or an alkylphosphinic acid alkyl ester and then hydrolytically splitting the thiazolidinyl phosphonic acid dialkyl ester or thiazolidinyl alkylphosphinic acid alkyl ester. The thiazolidinyl compounds are new compounds. The 1-amino-2-mercapto-2-methylpropyl phosphonic acid and the 1-amino-2-mercapto-2-methylpropyl alkylphosphinic acids are needed for pharmaceutical purposes.
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申请公布号 |
US4524211(A) |
申请公布日期 |
1985.06.18 |
申请号 |
US19830552103 |
申请日期 |
1983.11.16 |
申请人 |
DEGUSSA AKTIENGESELLSCHAFT |
发明人 |
DRAUZ, KARLHEINZ;KOBAN, HANS G.;MARTENS, JUERGEN;SCHWARZE, WERNER |
分类号 |
C07F9/30;C07F9/38;C07F9/40;C07F9/6539;(IPC1-7):C07F9/30;C07F9/65 |
主分类号 |
C07F9/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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