发明名称 NOVEL N-(2,10-DIOXA-TRICYCLO-(5,3,1,03,8)-UNDECAN-5-YL) -TRYPTAMINE DERIVATIVE, MANUFACTURE AND HYPOTENSIVE DRUG
摘要 <p>N-(2,10-dioxa-tricyclo-[5,3,1,03,8]-undecane-5-yl)-tryptamine compounds corresponding to the formula <IMAGE> I with blood-pressure lowering effects, a method of producing such compounds and pharmaceutical compositions incorporating such compounds, wherein R1 is hydrogen, a benzyl or lower alkyl group; R2 is a lower alkyl or lower alkanoyl group; R3 is hydrogen or a lower alkyl group; R4 is hydrogen, benzyloxy, hydroxy or a lower alkoxy group; R5 is hydrogen, benzyloxy, hydroxy or a lower alkoxy group; and A and B either are both hydrogen or together represent a bond between their respective carbons.</p>
申请公布号 JPS60105678(A) 申请公布日期 1985.06.11
申请号 JP19840204191 申请日期 1984.10.01
申请人 KARI HIEMII FUARUMA GMBH 发明人 PEETAA BUIRIBUROOTO TEIISU;SAMUERU DABUIDO;URURIHI KIYUURU;GERUTO BUTSUSHIYUMAN;PEETAA FURETSUKAA
分类号 A61K31/35;A61K31/357;A61P9/12;C07D319/00;C07D493/08 主分类号 A61K31/35
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