摘要 |
Antibacterial activity is exhibited by, optionally further substituted, (3 acylamino)-2-azetidinones having in the 1-position a group of the formula <IMAGE> or a salt or ester thereof wherein R5 and R6 are the same or different and each is hydrogen, halogen, hydroxy, alkoxy, alkylthio, alkyl, substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, (cycloalkyl)alkyl, (cycloalkenyl)alkyl, phenyl, substituted phenyl, phenylalkyl or (substituted phenyl)alkyl or together R5 and R6 can be =CZ1Z2 wherein Z1 and Z2 are the same or different and each is hydrogen, alkyl, phenyl, or substituted phenyl: and R7 is hydrogen and R8 is hydrogen, hydroxy, alkoxy, alkanoyloxy, or halogen, or together R7 and R8 can be =CZ1Z2 or =O. |