发明名称 |
Verfahren zur Herstellung von 2-(substituierten-Benzyl)-cyanessigsäureestern |
摘要 |
<p>(A) alpha-Amino-acids of general formula:- (I) R4 and R5 = H and/or alkyl or, when R4 and R5 are in o-position, may together form a methylene group. M = alkoxy, amino or hydroxy n = 0, 1 or 2. (B) Acid addition salts of (I) with organic and inorganic acids. (C) Intermediates in the synthesis of (I) (see "Preparation") Decarboxylase-inhibitors in man and mammals. Also very valuable anti-hypertensive agents which may be used in cases of virulent hypertension. May also be used as intermediates in the synthesis of norepinephrinic cpds., which may be used as pressor-agents.</p> |
申请公布号 |
CH501592(A) |
申请公布日期 |
1971.01.15 |
申请号 |
CH19690011483 |
申请日期 |
1965.03.03 |
申请人 |
MERCK & CO., INC. |
发明人 |
SLETZINGER,MEYER;ARMOND FIRESTONE,RAYMOND;FLOYD REINHOLD,DONALD |
分类号 |
A61K31/135;C07C255/32;C07C255/53;C07D317/60;(IPC1-7):C07C101/30 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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