发明名称 Verfahren zur Herstellung von 2-(substituierten-Benzyl)-cyanessigsäureestern
摘要 <p>(A) alpha-Amino-acids of general formula:- (I) R4 and R5 = H and/or alkyl or, when R4 and R5 are in o-position, may together form a methylene group. M = alkoxy, amino or hydroxy n = 0, 1 or 2. (B) Acid addition salts of (I) with organic and inorganic acids. (C) Intermediates in the synthesis of (I) (see "Preparation") Decarboxylase-inhibitors in man and mammals. Also very valuable anti-hypertensive agents which may be used in cases of virulent hypertension. May also be used as intermediates in the synthesis of norepinephrinic cpds., which may be used as pressor-agents.</p>
申请公布号 CH501592(A) 申请公布日期 1971.01.15
申请号 CH19690011483 申请日期 1965.03.03
申请人 MERCK & CO., INC. 发明人 SLETZINGER,MEYER;ARMOND FIRESTONE,RAYMOND;FLOYD REINHOLD,DONALD
分类号 A61K31/135;C07C255/32;C07C255/53;C07D317/60;(IPC1-7):C07C101/30 主分类号 A61K31/135
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