PROCESS FOR PREPARING NEW CEPHEM COMPOUNDS

摘要

Cephalosporins I (R1 = H, CHO) are claimed. I (R1 = CHO) was prepd. from 7-amino-3-(1-allyl-5-tetrazolylthiomethyl)-3-cephem4-carboxylic acid (II) and syn-2-allyloxyimino-2-(2-formamido4-thiazolyl)acetic acid (III) and was deformylated. II was prepd. from Na cephalosporin C and 1-allyl-5-tetrazolethiol. III was obtained from 2-(2-formamido- 4-thiazolyl)glyoxylic acid and allyloxyamine-HCl. Many other title compds. were prepd. and tested for bactericidal activity.