Preparation of anthralin solutions or suspensions in aromatic esters and their use for diseases of the skin and nails

摘要

An oxidation-stable composition is useful for the treatment of diseases of the skin and nails, which comprises a solution of dispersion of anthralin in an aromatic ester of the formula: <IMAGE> wherein R represents H, OH, CH3, or OCH3, n is 1 or 2; R1 represents a linear or branched alkyl radical having 1 to 18 carbon atoms; a cycloalkyl radical having 4 to 6 carbon atoms which is optionally substituted by an alkyl radical having 1 to 3 carbon atoms; an arylalkyl or arylalkenyl radical in which the alkyl or alkenyl radical has 1 to 3 carbon atoms; or a phenyl radical optionally substituted by an alkyl radical having 1 to 3 carbon atoms or by an alkoxy radical having 1 or 2 carbon atoms; X represents the divalent radical -CH2-, -CH2-CH2-, or -CH=C-; and t is 0 or 1.