The present invention is concerned with the simultaneous formation and encapsulation of small particles from aqueous solutions of compounds whose solubility is greater at a first pH than at a second pH. The process is preferably used to prepare a readily soluble encapsulated pharmaceutically active compound.
申请公布号
NO850635(A)
申请公布日期
1985.02.18
申请号
NO19850000635
申请日期
1985.02.18
申请人
OHIO STATE UNIV RESEARCH FOUNDATION,
发明人
FRANK, SYLVAN GERALD,;CHEN, CHIH-MING JAMES,;PANTHUVANICH, SIRIPORN,;BRODIN, ARNE FOLKE,