发明名称 SULFONIUM DERIVATIVE AND ITS PREPARATION
摘要 NEW MATERIAL:The compound of formula I (R1 and R2 are lower alkyl; R3 is H or lower alkyl; R4 is H, lower alkyl, cycloalkyl, carboxymethyl, etc.; R3 and R4 may together form a methylene chain which may together with N bonded thereto form a heterocyclic group; n is 1-3; Y is acid residue). EXAMPLE:Dimethyl-2-cyclohexylcarbamoylethylsulfonium p-toluenesulfonate. USE:It has antiallergic, carcinostatic, anti-inflammatory, analgesic and immunoregulating activities, and is useful as pharmaceuticals and agricultural chemicals. PREPARATION:The compound of formula I can be prepared by reacting the sulfide compound of formula II with the compound of formula R2Y in a solvent or in the absence of solvent at -30-+150 deg.C for about 0.5-72hr.
申请公布号 JPS604165(A) 申请公布日期 1985.01.10
申请号 JP19830112460 申请日期 1983.06.21
申请人 TAIHOU YAKUHIN KOGYO KK 发明人 EDA SHIYOUEI;HORI MIKIO;MATSUURA NAOSUKE;YASUMOTO SANJI;MATSUMOTO HIROSHI;YAMAWAKI ICHIROU
分类号 C07D295/18;A61K31/16;A61K31/165;A61K31/195;A61K31/22;A61K31/34;A61K31/341;A61K31/395;A61K31/41;A61K31/445;A61P37/08;C07C67/00;C07C325/00;C07C381/12;C07D257/04;C07D257/06;C07D307/32 主分类号 C07D295/18
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