| 摘要 |
<p>N- AD3-morpholinyl-(4)-1-methylpropyl BD-amines and N- AD3-azolyl-(4)-1-methylpropyl BD-N-alkylamines having the general formula (I), wherein R1 represents separated linear alkyl rests containing from 8 to 14 atoms of carbon or mixtures thereof, a rest n-dodecyloxytrimethylene or n-dodecyl/tetradecylaminotrimethylene and wherein R2 represents optionally alkyl substituted cyclic hydrocarbon rests with five or six chain branchings, containing an hydrogen atom and optionally other hetero atoms, as well as salts thereof with organic and inorganic acids. The present invention further relates to a process for the preparation of the compounds having the general formula (I), characterized in that the cyclic hydrocarbons with five or six chain branchings, which are optionally alkyl substituted, and containing a nitrogen atom and optionally other hetero atoms, having the formula R2H, wherein R2 has the same representation as hereabove, are replaced by methylvinylketone and in that the resultant substituted ethylmethylketone, at a higher temperature and in solution in the presence of molecular hydrogen and a catalyst, is replaced by a long chain amine having the formula R1NH2, wherein R1 has the same representation as hereabove. Finally the present invention relates to the utilization of compounds having the general formula (I) as antimicrobial agents. </p> |
