Novel glycolic acid type platinum complexes.

摘要

Novel platinum complexes of the glycolic acid type having potent antitumor activity and high water solubility together with low nephrotoxicity and a pharmaceutical composition containing one or more said compounds together with one or more carriers, diluents or excipients are provided. They can be administered parenterally to patients suffering from malignant tumors.

They are prepared by passing nitrato-platinum complexes of amines through anion exchange resins and subsequent reaction with glycolic acids.